Antibody filters treat pre‑eclampsia

A Nature Medicine trial used blood filters coated with antibodies that bind and remove the placenta‑derived protein sFlt‑1 from maternal circulation. Removing sFlt‑1 lowered maternal blood pressure, prolonged pregnancies by days to weeks, and produced healthier neonatal outcomes without introducing new drugs to the fetus. Some patients showed transient rebounds in sFlt‑1 but levels later stabilized. — If validated, a non‑pharmacological, extracorporeal approach to treating pre‑eclampsia could reduce emergency C‑sections, lower NICU burden, and change regulatory and clinical standards for managing high‑risk pregnancies.