Dichotomania in embryo claims

Updated: 2026.01.05 24D ago 1 sources
Embryo‑selection marketing and risk claims exploit 'dichotomania' — the habit of converting continuous traits into sharp disease/no‑disease cutoffs — to report large relative risk reductions that correspond to negligible average phenotype change. Regulators, clinicians and journalists should require vendors to report both the expected absolute phenotypic shift and the distributional mechanics (how many individuals sit near the threshold) rather than only relative risk percentages. — Standardizing how genetic‑risk reductions are framed will prevent consumer deception, inform clinical consent, and guide policy on the ethical use and advertising of polygenic embryo selection.

Sources

What we talk about when we talk about risk - by Sasha Gusev
2026.01.05 100% relevant
Sasha Gusev’s article uses BMI>40 and the liability‑threshold model to show a tiny mean BMI reduction maps to a large percent 'risk reduction', exemplifying the dichotomania problem in current embryo‑selection marketing.
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