Fever as glycine deficiency

The author hypothesizes that some fevers might be a downstream consequence of insufficient glycine — an amino acid implicated in mitochondrial repair and core‑temperature regulation via NMDA signaling — rather than only a direct pathogen‑triggered defense. If true, mild glycine supplementation could change how we interpret and manage certain febrile responses, but current evidence is sparse and inconsistent. — If validated, the idea would affect public health guidance on fever management, supplement use, and how mechanistic hypotheses spread in lay communities.