Fructose as hormone framework

A scientific reframing that treats dietary fructose not merely as calories but as a signalling molecule that tells the liver to make fat and to trigger a famine response. The review argues this signalling explains why small, repeated doses (e.g., sugary drinks) drive metabolic disease differently than equivalent calories from other nutrients. — If accepted, this changes how public health guidance, food labelling, taxation, and industry practices are justified — shifting focus from 'calories in/out' to chemical signalling effects of specific sugars.