Neurotransmitters as Body‑Wide Communicators

Updated: 2026.03.11 6H ago 1 sources
Molecules commonly labeled 'neurotransmitters' (like dopamine, GABA, glutamate, oxytocin) operate outside the nervous system — in gut cells, muscles, kidneys, immune tissues and even in microbes and plants — mediating physiological processes that affect health. Reframing them as general 'chemical biomediators' reveals evolutionary continuity and suggests that diet, drugs, and the microbiome can alter their systemic roles. — This reframing shifts how medicine, public‑health guidance, and drug regulation should evaluate side effects and therapeutic targets beyond the brain.

Sources

The Secret Life of Neurotransmitters
Olivia Hewitt 2026.03.11 100% relevant
The article cites sea sponges using GABA and glutamate for contraction, muscle cells making GABA/glutamate to control contraction, dopamine acting in kidneys and immune contexts, and plant/microbial release of the same molecules; it also quotes Victoria Roshchina urging the term 'chemical biomediators.'
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