One Drug, Multiple Addictions

GLP‑1 drugs appear to dampen reward signaling tied not only to alcohol but also to nicotine and cocaine. That hints at a cross‑addiction pharmacology where a metabolic therapy blunts multiple compulsive behaviors by reducing cue reactivity, not general activity. — If a single pathway modulates several addictions, funding and policy may pivot from siloed programs to broad anti‑addiction pharmacotherapies.