Overdose Deaths Drop Since 2022 Peak

CDC provisional counts compiled on the page show a sharp peak of roughly 110,900 U.S. overdose deaths in 2022 and an estimated ~71,500 deaths in the 12 months ending Oct 31, 2025. If the provisional decline proves robust (not a reporting artifact), it would mark a rapid shift in a decades‑long trend dominated by synthetic opioids. — A credible reversal or large decline in overdose deaths would change priorities for federal and state public‑health spending, policing and supply‑side policy, and the public narrative about the opioid crisis.