Overdose Deaths Fall Since 2022 Peak

CDC‑based totals compiled on the page show U.S. drug‑overdose deaths peaking around 110,900 in 2022 and falling to a provisional ~71,500 for the 12 months ending Oct 31, 2025 (predicted counts). The data also underline that most recent deaths involve synthetic opioids (fentanyl), so the decline coexists with continued dominance of fentanyl in fatal overdoses. — If validated, a meaningful post‑2022 decline would change the urgency and design of policy responses (supply interdiction, harm reduction, treatment scale‑up) and test theories about what drove the peak (supply shocks, polysubstance trends, pandemic effects).