Overdose deaths fell after 2022 peak

Updated: 2026.11.03 2H ago 1 sources
CDC provisional counts show U.S. drug-overdose deaths peaked around 2022 (~110,900) and have fallen in subsequent provisional tallies (roughly 66,500 in the 12 months ending May 31, 2026), but rates remain historically high (about 19.4 per 100,000 in that 12‑month window). The decline is measurable but incomplete, and fentanyl (synthetic opioids) still accounts for the majority of opioid-involved fatalities in recent years. — If the epidemic is partially retreating, policymakers risk complacency; the data should reframe debates about continuing harm‑reduction, supply‑control, and treatment investments.

Sources

United States drug overdose death rates and totals over time - Wikipedia
2026.11.03 100% relevant
CDC provisional counts cited on the page: peak ~110,900 deaths in 2022 and 66,500 deaths in the 12 months ending May 31, 2026 (CDC predicted provisional counts and population denominators).
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