Schizophrenia should be treated and researched as a set of related but distinct biological and clinical subtypes rather than a single illness driven mainly by excess dopamine. Doing so would shift research toward precision biomarkers, targeted pharmacology, and neurostimulation tailored to specific deficits (cognitive, negative, psychotic) instead of one‑size‑fits‑all antipsychotics.
— Framing schizophrenia as heterogeneous would redirect funding, clinical guidelines, disability policy and drug development toward subtype‑specific solutions with better functional outcomes.
Seeds of Science
2026.04.29
100% relevant
Clinical vignette of 'Jaden' plus the article's critique that dopamine‑blocking drugs reduce psychosis without restoring reasoning, planning, or social function exemplify the mismatch between current treatments and the syndrome's broader impairments.
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