A Neurology study of 12,772 adults found that higher intake of common low‑/no‑calorie sweeteners (e.g., aspartame, saccharin, erythritol, xylitol, sorbitol) was associated with faster cognitive decline over time. Intake levels ranged from ~20 mg/day in the lowest group to ~191 mg/day in the highest (about a diet soda’s worth for aspartame). One naturally occurring sweetener found in fruit, cacao, and dairy was not linked to the same effect. The study is observational, so it shows association, not causation.
— If confirmed, this evidence could shift dietary guidance, labeling, and consumer behavior around 'diet' foods and beverages.
Sara Kiley Watson
2025.09.22
100% relevant
Claudia Kimie Suemoto (University of São Paulo) and coauthors’ Neurology analysis cited in the article, with reported intake brackets and sweetener list.
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