Ultrasound Opens Brain to Therapy

Focused ultrasound can temporarily open the blood‑brain barrier to deliver drugs and, in mouse models of cerebral cavernous malformation, even appears to halt lesion growth without medication. Because the approach is noninvasive and already used in other indications, neurosurgeons are designing clinical trials to test it in CCM patients. — If validated, this could transform treatment pathways for neurodegenerative, oncologic, and rare brain diseases by replacing risky surgery or ineffective delivery methods with a scalable, device‑based therapy.