Microsoft’s CLIO orchestration boosted GPT‑4.1 accuracy on text‑only biomedical questions from 8.55% to 22.37%, beating o3‑high without retraining the base model. Structured, self‑adaptive prompting can unlock large capability gains.
— If orchestration layers can leapfrog raw models, governance and procurement must evaluate whole systems, not just base model versions.
msmash
2025.09.29
50% relevant
By shipping orchestration primitives (VMs, memory, multi‑agent) that enable complex tool use and autonomous workflows, Anthropic underscores that system‑level tooling can unlock big capability jumps alongside base‑model gains.
BeauHD
2025.09.10
62% relevant
Microsoft blending Anthropic and OpenAI inside Office reflects a system‑level, model‑agnostic approach where orchestration and picking 'the right model for the task' can matter more than upgrading a single base model—echoing the idea that tooling and routing can outpace raw model advances.
Alexander Kruel
2025.08.11
100% relevant
Microsoft research blog and numbers cited: CLIO raised GPT‑4.1 from 8.55% to 22.37% on 'Humanity’s Last Exam'.