Family DNA Improves Embryo Scoring

Family‑based imputation (ImputePGTA) and using relatives' genotypes substantially raise the accuracy of polygenic scores for embryos compared with single‑sample methods. That technical step increases the expected benefit of embryo selection for complex traits and exposes limits where admixed populations or missing heritability reduce gains. — If family‑level methods become standard in clinics, embryo selection shifts from low‑power to meaningfully predictive, forcing urgent policy and ethical responses on access, inequality, and regulatory oversight.